Description

Tretinoin Cream

Tretinoin cream 0.05mg is a vitamin A derivative that is used to treat acne vulgaris and some types of promyelocytic leukemia, as well as various other skin conditions in over-the-counter medications.

Tretinoin Cream USP, 0.05% is used to treat acne vulgaris conditions. Tretinoin Cream contains tretinoin at 0.05% by weight, butylated hydroxytoluene, isopropyl myristate, polyoxyl stearate type II, purified water, sorbic acid, stearic acid, stearyl alcohol and xanthan gum in a hydrophilic cream vehicle.

Buy Related Products at Telebrands.pk

Tretinoin History And Background:

Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of vitamin A (retinol). It is an oxidation product of vitamin A metabolism in the body. In the human circulation, tretinoin is normally present. Found in very low concentrations, approximately 4 to 14 nmol/L.

Tretinoin exhibits anti-inflammatory, antineoplastic, antioxidant, and free radical-scavenging activities. It has been used for many years to treat a variety of skin conditions ranging from acne to various skin conditions. Wrinkles and activates nuclear receptors to regulate epithelial cell growth and differentiation.

Tretinoin Cream Benefits And Uses:

• Tretinoin is a vitamin A derivative that promotes cell production, proliferation and differentiation.
• When used topically, tretinoin regulates epidermal cell turnover and collagen production.
• It also prevents collagen loss, reduces inflammation, and inhibits the induction of matrix metalloproteinases (MMP), which are enzymes that break down collagen and elastic fibers.
• Tretinoin at doses ranging from 0.001% to 0.1% was associated with improvement in imaging and clinical signs of fine wrinkles, increased epidermal thickness, compaction of the stratum corneum, and decreased melanin content. . and proliferation, promotion of epidermal hyperplasia, and angiogenesis.
• Tretinoin exhibits antineoplastic activity when administered orally.
• Tretinoin was shown to induce differentiation in tumor cells.
• It induced cytodifferentiation and reduced acute promyelocytic leukemia (APL) cell proliferation in culture and in vivo.
• In patients with APL, tretinoin promoted early maturation of primitive promyelocytes derived from a leukemic clone, followed by repopulation of the bone marrow and peripheral blood by normal, polyclonal hematopoietic cells in patients achieving complete remission.

Tretinoin Cream 0.05mg Usage:

During the first few weeks of using tretinoin, your acne may appear worse as the medicine works on the pimples that form inside the skin. It may take 8-12 weeks to feel the results of this medicine.

Use it regularly to get maximum benefit from it. To help you remember, use it at the same time every day. Do not overdose or use more often than recommended. Your skin won’t improve as quickly, and you’ll be more prone to redness, peeling, and pain.

This medicine is available in various strengths and forms (eg, gel, cream, solution). The best type of medication to use will depend on your skin condition and your response to treatment. Tell your doctor if your condition persists or worsens.

Tretinoin Vs Adapalene:

Adapalene is also topical retinoid with FDA approval for the treatment of acne vulgaris. Retinoids are derivatives of vitamin A that are usually expressed by species with increased affinity for the retinoic acid receptor (RAR) with subsequent species. Medical professionals use retinoids to treat a variety of skin conditions.

Adapalene also has several off-label therapeutic applications, including the treatment of verrucae, molluscum contagiosum, Darier disease, Fox-Fordyce disease, Dowling-Degos disease, photoaging, pigmentary disorders, actinic keratoses, and alopecia areata. This activity outlines indications, contraindications, interactions, monitoring, and other therapeutic information for members of an interprofessional team in the care of patients on adapalene therapy.